Mechanistic and machine learning models design human gut consortia that robustly inhibit Clostridioides difficile
Hanhyeok Im, Yiyi Liu, Jaron C. Thompson, Gabriel I Miranda-Contreras, Kaixiang Loke, Rebecca Bacon, Lauren Lucas, Daniel Amador‐Noguez, Simon M. Gray, Ophelia S. Venturelli
The paper designs synthetic gut microbial communities using mechanistic and machine learning models to robustly inhibit C. difficile growth in vitro and in vivo.
bioRxiv · Aug 5, 2026 · PreprintSystems Biology