Hanhyeok Im

The paper designs synthetic gut microbial communities using mechanistic and machine learning models to robustly inhibit C. difficile growth in vitro and in vivo.

The paper demonstrates population cycles in a cross-feeding microbial community using an engineered system and a nonlinear dynamical model.

This study shows how human gut microbiota interactions influence the long-term growth and evolutionary adaptations of C. difficile, including metabolic shifts and reduced disease severity.