Author

Kaiyuan Zhang

Chinese Academy of SciencesPrimary ORCID profile (0000-0002-6594-9247 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Kaiyuan ZhangiD1 paper

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Fang WangiD· 1 shared Fuyou GuoiD· 1 shared Junlei ChangiD· 1 shared Mengzhao FengiD· 1 shared Min YuiD· 1 shared Qi Qin· 1 shared Zhihua LiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Fang WangORCID

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1 paper

Recent·Most cited

Sphk1-S1P signaling drives blood-brain barrier breakdown after intracerebral hemorrhage via HIF-1α-dependent upregulation of Bsg-MMP-9

Mengzhao Feng, Qi Qin, Kaiyuan Zhang, Min Yu, Fang Wang, Zhihua Li, Junlei Chang, Fuyou Guo

This study identifies Sphk1-S1P signaling as a driver of BBB breakdown after ICH through HIF-1α-dependent upregulation of Bsg-MMP-9, offering a therapeutic target.

bioRxiv · May 6, 2026 · PreprintCell Biology