Histone deacetylase inhibitors correct the cholesterol storage defect in most NPC1 mutant cells
Nina H Pipalia, Kanagaraj Subramanian, Shu Mao, William E Balch, Frederick R Maxfield
This study shows that HDAC inhibitors correct cholesterol storage defects in most NPC1 mutant cells by increasing mutant NPC1 protein expression.
bioRxiv · Sep 23, 2016Cell Biology