Cell BiologybioRxiv
Histone deacetylase inhibitors correct the cholesterol storage defect in most NPC1 mutant cells
Nina H Pipalia, Kanagaraj Subramanian, Shu Mao…·Frederick R Maxfield
This study shows that HDAC inhibitors correct cholesterol storage defects in most NPC1 mutant cells by increasing mutant NPC1 protein expression.
DOI 10.1194/jlr.m072140