Author

Kanchan Chaggar

University College London

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Neuroscience· 1

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Approach:experimental assay· 1

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ANNETTE C. DOLPHINiD· 1 shared Hideaki NagaseiD· 1 shared Ivan KaduriniD· 1 shared Joseph I. J. EllawayiD· 1 shared Karen M. PageiD· 1 shared Linda TroebergiD· 1 shared Shehrazade Dahimène· 1 shared

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2021-2021 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 paper

Recent·Most cited

Identification that ADAM17 mediates proteolytic maturation of calcium channel auxiliary α2δ subunits, and enables calcium current enhancement

Ivan Kadurin, Shehrazade Dahimène, Karen M. Page, Joseph I. J. Ellaway, Kanchan Chaggar, Linda Troeberg, Hideaki Nagase, ANNETTE C. DOLPHIN

This study identifies ADAM17 as a protease essential for proteolytic maturation of 2{delta} subunits, which enhances calcium currents and is relevant to neuropathic pain.

bioRxiv · Apr 29, 2021 · PreprintNeuroscience