Incorporation of active cell-free expression lysates in chitosan coated alginate microcapsules
Farah A. Merchant, Flutur Latifi, Djellza Sylaj, Emily S Wheeler, Kara Loots, Matthew A. Coleman, Vjollca H. Konjufca, Steven A. Hoang-Phou
This paper demonstrates that chitosan-coated alginate microcapsules can protect cell-free gene expression lysates and proteins from degradation in the GI tract and enable controlled release in simulated intestinal conditions.
bioRxiv · Jun 9, 2026 · PreprintBioengineering