Author

Kari S. Lee

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Chuangchuang ZhangiD· 1 shared Gene Wei-Ming YeoiD· 1 shared Hongshuai LiuiD· 1 shared Jiaxu CheniD· 1 shared Kathryn H. MorelliiD· 1 shared Krysten L. JonesiD· 1 shared Maya L. GosztylaiD· 1 shared Qian WuiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Chuangchuang ZhangORCID

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1 paper

Recent·Most cited

RNA-Targeting CRISPR/Cas13d System Eliminates Disease-Related Phenotypes in Pre-clinical Models of Huntington's Disease.

Kathryn H. Morelli, Qian Wu, Maya L. Gosztyla, Hongshuai Liu, Chuangchuang Zhang, Jiaxu Chen, Ryan J. Marina, Kari S. Lee, Krysten L. Jones, Wenzhen Duan, Gene Wei-Ming Yeo

This study develops a CRISPR-Cas13d system targeting CAG-expanded HTT RNA in HD models, reducing mutant mRNA and reversing disease phenotypes without significant off-target effects.

bioRxiv · Jan 23, 2022 · PreprintNeuroscience