Author

Kathryn H. Morelli

Jackson LaboratoryORCID 0000-0002-3123-5369Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1

Frequent Co-Authors

Abigail L. D. TadeneviD· 1 shared Brian Robert HoffmanniD· 1 shared Carol J. BultiD· 1 shared Chuangchuang ZhangiD· 1 shared Courtney L. HattoniD· 1 shared David G. Schroeder· 1 shared G C Murray· 1 shared Gene Wei-Ming YeoiD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetics

Abigail L. D. TadenevORCID

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2 papers

Recent·Most cited

GeneticsHuman Molecular GeneticsPeer-reviewedJul 7, 2022

Mouse models of NADK2 deficiency analyzed for metabolic and gene expression changes to elucidate pathophysiology

G C Murray, Preeti Bais, Courtney L. Hatton…·Robert W. Burgess

This study analyzes NADK2 deficiency in mouse models to identify metabolic and gene expression changes, revealing similarities and differences with another neurological disease model.

9 citations

mousebulk RNA-seq

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NeurosciencebioRxivPreprintJan 23, 2022

RNA-Targeting CRISPR/Cas13d System Eliminates Disease-Related Phenotypes in Pre-clinical Models of Huntington's Disease.

Kathryn H. Morelli, Qian Wu, Maya L. Gosztyla…·Gene Wei-Ming Yeo

This study develops a CRISPR-Cas13d system targeting CAG-expanded HTT RNA in HD models, reducing mutant mRNA and reversing disease phenotypes without significant off-target effects.

3 citations

mouseexperimental assay

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