Murine astrotactins 1 and 2 have similar membrane topology and mature via endoproteolytic cleavage catalyzed by signal peptidase
Patricia Lara, Åsa Tellgren‐Roth, Hourinaz Behesti, Zachi Horn, Nina Schiller, Karl Enquist, Malin Cammenberg, Amanda Liljenström, Mary E. Hatten, Gunnar von HEIJNE, IngMarie Nilsson
This study maps the membrane topology and maturation mechanism of murine Astn1 and Astn2, showing they mature via endoproteolytic cleavage by signal peptidase.
Journal of Biological Chemistry · Jan 29, 2019Peer-reviewedNeuroscience