Capturing early events in aryl hydrocarbon receptor activation using two complementary protein-protein interaction assays
Tim Kuhn, Sarka Tumova, Nicholas Zacharewski, Paul Averdung, Bianca Berdel, Karl-Heinz Kellner, Stefan Pusch, Marek Jindra, Christiane A. Opitz, Mirja Tamara Prentzell
This paper introduces two protein-protein interaction assays to measure AHR activation independent of transcriptional output, capturing agonist- and antagonist-dependent modulation across ligands and cell types.
bioRxiv · Jun 22, 2026 · PreprintBiochemistry