Stefan Pusch

Capturing early events in aryl hydrocarbon receptor activation using two complementary protein-protein interaction assays

This paper introduces two protein-protein interaction assays to measure AHR activation independent of transcriptional output, capturing agonist- and antagonist-dependent modulation across ligands and cell types.

IDH-mutant gliomas arise from glial progenitor cells harboring the initial driver mutation

This study identifies glial progenitor cells as the cell-of-origin for IDH-mutant gliomas by analyzing patient tissues and mouse models.