One-Pot Isothermal Linear Amplification and Cas12a-based Nucleic Acid Detection
Selma Sinan, Remy M. Kooistra, Karunya Rajaraman, Zeba Islam, Damian Madan, Eric A. Nalefski, Ilya J. Finkelstein
The paper develops CATNAP, a single-reaction method combining isothermal DNA amplification and Cas12a detection for sensitive HPV detection in low-resource settings.
ACS Synthetic Biology · Nov 17, 2025Peer-reviewedBiochemistry