Author

Selma Sinan

The University of Texas at AustinORCID 0000-0002-0632-3658Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Ilya J. FinkelsteiniD· 2 shared Carlos ArguelloiD· 1 shared Chia‐Wei ChouiD· 1 shared Damian MadaniD· 1 shared Daphne SahayaiD· 1 shared Eric A. NalefskiiD· 1 shared Hung‐Che KuoiD· 1 shared Karunya Rajaraman· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Ilya J. FinkelsteinORCID

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2 papers

Recent·Most cited

Structural Basis for Target Discrimination and Activation by Cas13d

Chia‐Wei Chou, Selma Sinan, Hung‐Che Kuo, You-Chiun Chang, Carlos Arguello, Daphne Sahaya, Rick Russell, Ilya J. Finkelstein

This study reveals the structural basis for Cas13d's target discrimination and activation through cryo-EM structures and kinetic analysis of matched and mismatched RNA targets.

Science Advances · Aug 19, 2026Peer-reviewedBiochemistry

One-Pot Isothermal Linear Amplification and Cas12a-based Nucleic Acid Detection

Selma Sinan, Remy M. Kooistra, Karunya Rajaraman, Zeba Islam, Damian Madan, Eric A. Nalefski, Ilya J. Finkelstein

The paper develops CATNAP, a single-reaction method combining isothermal DNA amplification and Cas12a detection for sensitive HPV detection in low-resource settings.

ACS Synthetic Biology · Nov 17, 2025Peer-reviewedBiochemistry