Author

Katerina Growkova

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

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Cynthia WolbergeriD· 1 shared David Komander· 1 shared Marcello Clerici· 1 shared Marie Morrow· 1 shared Michael Morgan· 1 shared Michal Simicek· 1 shared Ming Yan· 1 shared Titia Sixma· 1 shared

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2017-2017 · peak 1/yr

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1 shared paperBiochemistry

Cynthia WolbergerORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintDec 22, 2017

Active site alanine substitutions can convert deubiquitinating enzymes into avid ubiquitin-binding domains

Marie Morrow, Michael Morgan, Marcello Clerici…·Cynthia Wolberger

The paper shows that replacing the catalytic cysteine in DUBs with alanine increases their ubiquitin binding affinity, potentially causing unintended physiological effects.

DOI 10.1101/238154

protein structureexperimental assay

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