Human senataxin uses distinct peripheral elements to unwind R-loops and act on RNA polymerase II
Matyas Lanicek, Katerina Sedova, Zdenka Hasanova, Odil Porrua, Marek Sebesta
This study identifies distinct peripheral elements in senataxin that mediate R-loop unwinding and RNA polymerase II regulation through structural and biochemical analyses.
bioRxiv · Nov 3, 2026 · PreprintBiochemistry