Queuosine glycosylation occurs after anticodon loop methylations and protects against stress-induced tRNA fragmentation
Ana C. de A. P. Schwarzer, Julia Dietzsch, Sabrina Stille, Nicolás Lemus-Diaz, Milan Erich, Eva Schoeller, Katharina Sievers, Achim Dickmanns, Ralf Ficner, Katherine E. Bohnsack, Claudia Höbartner, Markus T. Bohnsack
The paper investigates the hierarchical modification pathways of tRNA anticodon loop modifications and shows that Q34 glycosylation protects tRNAAsp from stress-induced fragmentation.
bioRxiv · Oct 10, 2026 · PreprintMolecular Biology