Katherine E. Bohnsack

The paper investigates the hierarchical modification pathways of tRNA anticodon loop modifications and shows that Q34 glycosylation protects tRNAAsp from stress-induced fragmentation.

The paper shows that phosphorylation of NOB1, an endoribonuclease, affects 18S rRNA processing and pre-rRNA levels during small subunit biogenesis.

The paper identifies RNA helicase partners of G-patch proteins and reveals distinct regulatory mechanisms by which they influence mRNA maturation.

The paper introduces chemical crosslinking with mass spectrometry and a new search engine, NuXL, to identify nucleic acid-protein crosslinks at amino acid resolution, enhancing structural analysis.

The paper identifies the molecular mechanisms by which ELAC2 processes nuclear and mitochondrial tRNAs, revealing distinct roles for TRMT10C and SDR5C1 in mitochondrial tRNA maturation.

The paper shows hypoxia reduces EXOSC10 SUMOylation, leading to its nuclear translocation and changes in mRNA transcriptome related to hypoxia.

The paper shows that RNA-controlled shuttling of Xrn1 and its decay factors regulates mRNA synthesis and decay, revealing a novel nuclear-initiated cytoplasmic decay pathway.

The paper examines m6A RNA methylation changes in mouse and human brains during aging and Alzheimer's disease, finding reduced m6A levels in synaptic transcripts and impaired synaptic protein synthesis.

This study defines the molecular mechanism of GTPase-mediated mitochondrial ribosome biogenesis and recycling using cryo-EM and biochemical approaches.