Achim Dickmanns

The paper investigates the hierarchical modification pathways of tRNA anticodon loop modifications and shows that Q34 glycosylation protects tRNAAsp from stress-induced fragmentation.

This study identifies Impβ as a regulator of actin polymerization, showing its role in stress fiber formation and cell migration independent of nuclear transport.

The paper identifies AKIRIN2 as a multivalent adaptor protein that coordinates proteasome nuclear import through a stepwise assembly of importin clusters.

The paper uses Alphafold3 to predict and validate the structure of the Imp{beta}/Imp7/H1 complex, showing H1 binds to Imp7 rather than Imp{beta} and identifying key interaction regions.

The paper introduces chemical crosslinking with mass spectrometry and a new search engine, NuXL, to identify nucleic acid-protein crosslinks at amino acid resolution, enhancing structural analysis.