Single cell spatial transcriptomic and translatomic profiling of dopaminergic neurons in health, aging and disease
Peter Kilfeather, Jia Hui Khoo, Katherina Wagner, Han Liang, Maria Claudia Caiazza, Yanru An, Xingju Zhang, Xiaoyan Chen, Natalie Connor‐Robson, Zhouchun Shang, Richard Wade‐Martins
The paper profiles spatial transcriptomic and translatomic data of dopaminergic neurons in young and old mice, identifying markers of aging and disease-related pathways, and highlights CASR as a novel regulator of dopaminergic calcium handling.
Cell Reports · Feb 21, 2024Peer-reviewedMolecular Biology