Ketamine rescues anhedonia by cell-type and input specific adaptations in the Nucleus Accumbens
Federica Lucantonio, Jacob Roeglin, Shuwen Li, Jaden Lu, Aleesha Shi, Katherine Czerpaniak, Francesca Romana Fiocchi, Leonardo Bontempi, Brenda C. Shields, Carlos A. Zarate, Michael R. Tadross, Marco Pignatelli
This study shows ketamine rescues stress-induced anhedonia in mice by cell-type-specific adaptations and input-specific synaptic changes in the nucleus accumbens.
Neuron · Mar 19, 2025Peer-reviewedNeuroscience