Cancer BiologybioRxivPreprint
Mechanisms underpinning osteosarcoma genome complexity and evolution
Jose Espejo Valle-Inclan, Solange De Noon, Katherine Trevers…·Isidro Cortes-Ciriano
This study identifies chromothripsis and a novel LTA chromothripsis mechanism driving genome complexity and evolution in osteosarcoma, with prognostic implications for high-grade tumors.
DOI 10.1101/2023.12.29.573403