A refined human linear B cell epitope map of Outer surface protein C (OspC) from the Lyme disease spirochete, Borreliella burgdorferi
Grace Freeman-Gallant, Kathleen A. McCarthy, Jennifer L. Yates, Karen E. Kulas, Michael J. Rudolph, David J. Vance, Nicholas John Mantis
The paper evaluates IgG reactivity to OspC-derived peptides in Lyme disease serum samples, identifying C10 as the most reactive epitope and highlighting complexities in B cell responses.
Pathogens and Immunity · Feb 14, 2025Peer-reviewedImmunology