Author

Kathryn L. Roche

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Biology Disciplines

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Microbiology· 1

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Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

Christopher E. MontiiD· 1 shared Eain A. MurphyiD· 1 shared Katie M. CataldoiD· 1 shared Ranjan K. DashiD· 1 shared Scott S. TerhuneiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperMicrobiology

Christopher E. MontiORCID

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1 paper

Recent·Most cited

The effective multiplicity of infection for HCMV depends on activity of the cellular 20S proteasome

Katie M. Cataldo, Kathryn L. Roche, Christopher E. Monti, Ranjan K. Dash, Eain A. Murphy, Scott S. Terhune

This study shows that proteasome inhibition reduces HCMV replication by lowering the effective multiplicity of infection, and synergizes with antiviral drugs.

Journal of Virology · Dec 10, 2024Peer-reviewedMicrobiology