Scott S. Terhune

This paper develops a data-driven computational model of the human cell cycle that predicts inhibitor effects and combination responses in silico.

This paper identifies UL138 as a viral protein that modulates host DNA repair pathways to maintain viral genome integrity during replication.

This study shows that proteasome inhibition reduces HCMV replication by lowering the effective multiplicity of infection, and synergizes with antiviral drugs.

This paper investigates how HCMV infection affects microtubule networks in human forebrain neurons and shows that stabilizing microtubules reduces syncytia formation and neurite retraction.

This study compares HCMV replication efficiency in epithelial cells using viruses produced from fibroblasts or epithelial cells, finding higher titer and syncytia formation with epithelial-derived virus.

This study shows that HCMV can infect and replicate in terminally differentiated human cortical neurons, causing structural and functional changes including altered calcium signaling and neurotransmission.

The paper investigates how the source of HCMV affects neuronal pathogenesis in cerebral organoids and shows that neutralizing antibodies and neurotropic factors can mitigate gene expression dysregulation.

The paper was withdrawn due to authorship disputes and is not intended for citation.