Vagus nerve stimulation accelerates motor learning through cholinergic modulation
Spencer G. Bowles, Jordan L. Hickman, Xiaoyu Peng, W. Ryan Williamson, Rongchen Huang, Kayden A. Washington, Dane Donegan, Cristin G. Welle
This study shows that vagus nerve stimulation (VNS) enhances motor learning in mice when paired with successful movement, but impairs learning when random, suggesting it reinforces outcome cues through cholinergic signaling.
bioRxiv · Oct 28, 2021 · PreprintNeuroscience