Cristin G. Welle

This study shows that myelin loss impairs movement efficiency and alters neuronal activity, with partial remyelination restoring some network metrics but not smooth movement.

The paper presents a miniaturized widefield microscope for high-speed voltage imaging in freely moving animals, achieving a peak-to-noise ratio >3 at 530 Hz.

This study shows that paired vagus nerve stimulation promotes remyelination and motor recovery after myelin loss by restoring myelin sheath patterns.

This study shows that vagus nerve stimulation (VNS) enhances motor learning in mice when paired with successful movement, but impairs learning when random, suggesting it reinforces outcome cues through cholinergic signaling.

CLARA is a closed-loop system for automated motor behavior analysis and stimulation in mice, showing that post-success vagus nerve stimulation improves motor performance.

This study shows that motor learning after partial remyelination enhances remyelination by increasing oligodendrogenesis and myelin sheath generation.

This study identifies novel biomarkers for traumatic brain injury by analyzing changes in neurovascular coupling using combined optical and electrophysiological measurements in a mouse model.