W. Ryan Williamson

Myelin Supports Cortical Circuit Function Underlying Skilled Movement

This study shows that myelin loss impairs movement efficiency and alters neuronal activity, with partial remyelination restoring some network metrics but not smooth movement.

REVEALS: An Open Source Multi Camera GUI For Rodent Behavior Acquisition

REVEALS is an open-source GUI for rodent behavior data acquisition using multiple cameras, validated with DeepLabCut for pose estimation in behavioral assays.

Miniscope Recording Calcium Signals at Hippocampus of Mice Navigating an Odor Plume

The paper describes a protocol to monitor mouse behavior and record calcium signals in hippocampal neurons during odor plume navigation, including surgery, imaging, data processing, and decoding of spatial paths.

Vagus nerve stimulation accelerates motor learning through cholinergic modulation

This study shows that vagus nerve stimulation (VNS) enhances motor learning in mice when paired with successful movement, but impairs learning when random, suggesting it reinforces outcome cues through cholinergic signaling.

Closed-loop automated reaching apparatus (CLARA) for interrogating motor systems

CLARA is a closed-loop system for automated motor behavior analysis and stimulation in mice, showing that post-success vagus nerve stimulation improves motor performance.

Unc-4 acts to promote neuronal identity and development of the take-off circuit in the Drosophila CNS

This study identifies the role of Unc-4 in promoting neuronal identity and development of the take-off circuit in the Drosophila CNS.