Increased GITRL impairs the function of MDSCs and exacerbates primary Sjögren’s syndrome
Jie Tian, Ke Rui, Yue Hong, Xiang Lin, Xiaohui Wang, Fan Xiao, Huaxi Xu, Liwei Lu, Shengjun Wang
This study shows that increased GITRL impairs MDSC function and worsens primary Sjögren’s syndrome in mice and patients.
bioRxiv · Jul 21, 2018 · PreprintImmunology