Author

Kellen Biesbrock

University of Wisconsin–Madison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Harshini CormatyiD· 1 shared John M. DenuiD· 1 shared Rupa SridharaniD· 1 shared Spencer A. HawsiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperBiochemistry

Harshini CormatyORCID

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1 paper

Recent·Most cited

dCas9 metabolic enzyme fusions modulate global and locus specific gene expression

Kellen Biesbrock, Spencer A. Haws, Harshini Cormaty, Rupa Sridharan, John M. Denu

This study introduces CRISPRm, a dCas9-metabolic enzyme fusion platform, to investigate how nuclear metabolic perturbations affect gene expression and chromatin states in HEK293T cells.

bioRxiv · May 10, 2026 · PreprintBiochemistry