A Hypomorphic Cystathionine β-Synthase Gene Contributes to Cavefish Eye Loss by Disrupting Optic Vasculature
Li Ma, Aniket V. Gore, Daniel Castranova, Janet Shi, Mandy Ng, Kelly A. Tomins, Corine M. van der Weele, Brant M. Weinstein, William R. Jeffery
This study identifies a mutation in the cbsa gene as a contributor to eye loss in cavefish by disrupting optic vasculature and causing hypoxia.
Nature Communications · Jun 2, 2020Peer-reviewedDevelopmental Biology