Author

Kelly Smith

University of Massachusetts Chan Medical SchoolPrimary ORCID profile (0000-0002-8283-9760 · 6 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Kelly SmithiD6 papers · The University of Melbourne

Biology Disciplines

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Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Jeanne Bentley LawrenceiD· 1 shared Lucas Javier SosaiD· 1 shared Melvys ValledoriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperDevelopmental Biology

Jeanne Bentley LawrenceORCID

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1 paper

Recent·Most cited

APP Dosage and Extracellular Domain Variants Drive Distinct Defects in Neurogenesis modeled in Down Syndrome iPS cells

Melvys Valledor, Kelly Smith, Jeanne Bentley Lawrence, Lucas Javier Sosa

This study investigates how APP dosage and extracellular domain variants affect neurogenesis in Down Syndrome iPSCs, finding distinct defects in terminal differentiation and neurite outgrowth.

bioRxiv · Aug 6, 2026 · PreprintDevelopmental Biology