The Indirect Pathway of the Basal Ganglia Promotes Negative Reinforcement, But Not Motor Suppression
Brian Robert Isett, Katrina P. Nguyen, Jenna C. Schwenk, Christen N Snyder, Kendra Adegbesan, Ugne Ziausyte, Aryn H. Gittis
This study shows that optogenetic stimulation of A2A-SPNs in the striatum drives negative reinforcement via the indirect pathway, not motor suppression.
bioRxiv · May 18, 2022 · PreprintNeuroscience