A steady state pool of calcium-dependent actin is maintained by Homer and controls epithelial mechanosensation
Kenji Matsuzawa, Makoto Suzuki, Yuma Cho, Ryoya Fujinaga, Junichi Ikenouchi
This paper identifies Homer and MUPP1/PatJ as regulators of calcium-dependent actin dynamics at the apical junctional complex, essential for epithelial mechanosensation and wound healing.
Proceedings of the National Academy of Sciences · Oct 24, 2025Peer-reviewedCell Biology