Author

Kennedie Lyles

Virginia Tech

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Neuroscience· 1

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

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Alexandra M. KalossiD· 1 shared Caroline de JageriD· 1 shared Hehuang XieiD· 1 shared Jackie Zhu· 1 shared John B. MatsoniD· 1 shared Michelle Hedrick TheusiD· 1 shared Nathalie A. GrootiD· 1 shared Yu‐Hui LiniD· 1 shared

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1 shared paperNeuroscience

Alexandra M. KalossORCID

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1 paper

Recent·Most cited

Tie2-Dependent Mechanisms Promote Leptomeningeal Collateral Remodeling and Reperfusion Following Stroke

Alexandra M. Kaloss, Caroline de Jager, Kennedie Lyles, Nathalie A. Groot, Jackie Zhu, Yu‐Hui Lin, Hehuang Xie, John B. Matson, Michelle Hedrick Theus

This study shows that Tie2 activation with Vasculotide enhances leptomeningeal collateral remodeling and reperfusion after stroke, while EphA4 inhibition mimics these effects, highlighting their opposing roles in vascular adaptation.

bioRxiv · Feb 28, 2025 · PreprintNeuroscience