Hehuang Xie

The paper identifies EGR1 binding at enhancers in excitatory neurons and shows its correlation with subtype-specific epigenetic regulation and gene pathways.

This study shows that Tie2 activation with Vasculotide enhances leptomeningeal collateral remodeling and reperfusion after stroke, while EphA4 inhibition mimics these effects, highlighting their opposing roles in vascular adaptation.

The paper uses machine learning to identify genes associated with neurological disorders from TBI, EEV, and OPNA by integrating transcriptomic data and analyzing gene expression patterns.

The paper identifies SHH signaling from retinal ganglion cells to thalamic astrocytes as essential for GABAergic interneuron migration into the visual thalamus.

The paper introduces native MOWChIP-seq, a low-input ChIP-seq method, and applies it to study protein binding differences between mouse brain regions.