Reversal of cardiac and skeletal manifestations of Duchenne muscular dystrophy by cardiosphere-derived cells and their exosomes in mdx dystrophic mice and in human Duchenne cardiomyocytes
Mark A. Aminzadeh, Russell G. Rogers, Kenneth Gouin, Mario Fournier, Rachel E. Tobin, Xuan Guan, Martin K. Childers, Allen M. Andres, David J. Taylor, Ahmed Ibrahim, Xiangming Ding, Angelo Torrente, Joshua M. Goldhaber, Ronald A. Victor, Roberta A. Gottlieb, , Eduardo Marbán
This study shows that cardiosphere-derived cells and their exosomes improve cardiac and skeletal muscle function in Duchenne muscular dystrophy models.
bioRxiv · Apr 20, 2017 · PreprintPhysiology