CRISPR-bind: a simple, custom CRISPR/dCas9-mediated labeling of genomic DNA for mapping in nanochannel arrays
Denghong Zhang, Saki Chan, Kenneth Sugerman, Joyce Lee, Ernest T. Lam, Sven Bocklandt, Han Cao, Alex R. Hastie
The paper introduces CRISPR-bind, a method using dCas9 to directly label genomic DNA with fluorescent CRISPR-dCas9 complexes for improved mapping and analysis.
bioRxiv · Jul 19, 2018 · PreprintGenomics