Author

Kent Brown

Michigan Technological University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 4

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Organism:rat· 4 Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:proteomics· 2 Approach:experimental assay· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Lanrong BiiD· 4 shared Zhiying Jenny ShaniD· 3 shared Brayden Storey· 2 shared Derrick Simet· 2 shared Emma Madsen· 2 shared Jacob Williams· 2 shared Muhammad Bilal Umar· 2 shared Yingjie Wang· 2 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

9 top collaborators · 25 mutual co-author links

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4 shared papersNeuroscience

Lanrong BiORCID

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4 papers

Recent·Most cited

Brain and kidney Extracellular Vesicle Morphology and Complementary Brain proteomics after Inflammatory Challenge

Kent Brown, Yingjie Wang, Zhiying Jenny Shan, Lanrong Bi

The paper compares brain and kidney extracellular vesicle morphology and proteomics after inflammatory challenge, identifying significant protein changes but noting limitations in causal conclusions.

bioRxiv · Oct 30, 2026 · PreprintNeuroscience

Exploratory Proteomics of Brain Extracellular Vesicle Enriched Preparations After LPS Challenge and miRNA Associated Vesicle Administration

Kent Brown, Yingjie Wang, Zhying Shan, Lanrong Bi

The paper uses proteomics to study protein changes in brain extracellular vesicles after LPS challenge and miRNA treatment in rats, identifying specific protein responses and potential markers.

bioRxiv · Oct 13, 2026 · PreprintNeuroscience

Spatial MALDI-MSI Reveals a Coordinated Vicious Cycle of Oxidative Membrane Damage and Ceramide-Driven Sphingolipid Dysregulation in the Chronically Neuroinflamed Brain

Kent Brown, Brayden Storey, Jacob Williams, Derrick Simet, Muhammad Bilal Umar, Emma Madsen, Zhiying Jenny Shan, Lanrong Bi

This study uses MALDI-MSI to show that chronic neuroinflammation causes spatial lipidomic changes in rat brains, including oxidative stress and sphingolipid dysregulation, particularly in the hippocampus and white matter.

bioRxiv · Jul 20, 2026 · PreprintNeuroscience

Age-Dependent Spatiotemporal Remodeling of Brain Sphingolipids During LPS-Induced Neuroinflammation: MALDI-MSI Reveals Accelerated Sphingomyelin Depletion and Sulfatide Accumulation Linked to Mitochondrial Oxidative Stress

Kent Brown, Brayden Storey, Jacob Williams, Derrick Simet, Muhammad Bilal Umar, Emma Madsen, Zhiying Jenny Shan, Lanrong Bi

This study uses MALDI-MSI to show age-dependent sphingolipid changes in rat brains after LPS, linking sphingomyelin loss and sulfatide gain to mitochondrial stress.

bioRxiv · Jul 1, 2026 · PreprintNeuroscience