Longitudinal tractography monitors cortical stroke-induced thalamocortical degeneration and neuroprotection by human iPSC-derived neurons
Sopiko Kartsivadze, Yu‐Ping Shen, Linda Jansson, Lucia Galan-Pintado, Keshav Kher, Sara Aviles, Michael E. Gottschalk, Aref Kalantari, Daniel Mertens, Raquel Martínez-Curiel, Markus Aswendt, Olle Lindvall, Sara Palma-Tortosa, Zaal Kokaia
This study uses longitudinal tractography to track thalamocortical degeneration after cortical stroke and shows that hiPSC-derived neuronal transplantation preserves thalamic connectivity and reduces atrophy.
bioRxiv · Mar 17, 2025 · PreprintNeuroscience