Using deep long-read RNAseq in Alzheimer's disease brain to assess medical relevance of RNA isoform diversity
Bernardo Aguzzoli Heberle, J. Anthony Brandon, Madeline L. Page, Kayla A. Nations, Ketsile I. Dikobe, Brendan J. White, Lacey A. Gordon, Grant A Fox, Mark E. Wadsworth, Patricia Hayes Doyle, Brittney A. Williams, Edward J. Fox, Anantharaman Shantaraman, Mina Ryten, Sara Goodwin, , Mark Ebbert
The paper uses long-read RNAseq to identify new RNA isoforms in Alzheimer's disease brain tissue and demonstrates their medical relevance.
Nature Biotechnology · May 22, 2024Peer-reviewedGenomics