Sustainable production of 2,3,5,6-Tetramethylpyrazine at high titer in engineered Corynebacterium glutamicum using statistical design of experiments
Aparajitha Srinivasan, Kevin Chen-Xiao, Deepanwita Banerjee, Asun M. Oka, Venkataramana R. Pidatala, Aymerick Eudes, Blake Alexander Simmons, Thomas Eng, Aindrila Mukhopadhyay
This paper engineers Corynebacterium glutamicum to produce 2,3,5,6-tetramethylpyrazine (TMP) at high titer using statistical design of experiments to optimize media composition.
Journal of Industrial Microbiology & Biotechnology · Jan 1, 2024Peer-reviewedSynthetic Biology