AA147 Alleviates Symptoms in a Mouse Model of Multiple Sclerosis by Reducing Oligodendrocyte Loss
Metin Aksu, Kevin Kaschke, Joseph R. Podojil, Ming‐Yi Chiang, Ian Steckler, Kody Bruce, Andrew C. Cogswell, Gwen Schulz, Jeffery W. Kelly, R. Luke Wiseman, Stephen D. Miller, Brian Popko, Yanan Chen
AA147 reduces oligodendrocyte loss and demyelination in a mouse model of MS by activating ATF6 and NRF2 pathways, improving clinical symptoms and microglia activation.
Glia · Feb 10, 2025Peer-reviewedNeuroscience