Wnt-Activated Immunoregulatory Myeloid Cells Prevent Relapse in Experimental Autoimmune Encephalomyelitis and Offer a Potential Therapeutic Strategy for Multiple Sclerosis
Anastasia Alkhimovitch, Stephen D. Miller, Igal Ifergan
This study shows that activating the Wnt signaling pathway in myeloid cells reduces neuroinflammation and disease severity in experimental autoimmune encephalomyelitis, suggesting a potential therapy for multiple sclerosis.
bioRxiv · Feb 16, 2025 · PreprintImmunology