Author

Kevin Lyons

Dana-Farber Cancer Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:DNA methylation· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Brad J. FortunatoiD· 2 shared Dory A. FreemaniD· 2 shared Hunter SavignanoiD· 2 shared Jacob E. BerchuckiD· 2 shared Ji-Heui SeoiD· 2 shared Jillian O’Toole· 2 shared John CanniffiD· 2 shared Karl SemaaniD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Brad J. FortunatoORCID

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2 papers

Recent·Most cited

Detection and monitoring of translocation renal cell carcinoma via plasma cell-free epigenomic profiling

Simon Garinet, Karl Semaan, Jiao Li, Ananthan Sadagopan, John Canniff, Noa Phillips, Kelly S. Klega, Medha Panday, Hunter Savignano, Matthew P. Davidsohn, Kevin Lyons, Alessandro Medda, Prateek Khanna, Mingkee Achom, Prathyusha Konda, , Srinivas Raghavan Viswanathan

This paper detects and monitors translocation renal cell carcinoma (tRCC) using plasma cell-free epigenomic profiling, achieving high accuracy in distinguishing tRCC from other cancers and healthy controls.

Journal of Clinical Investigation · Feb 1, 2026Peer-reviewedGenomics

Epigenomic signatures as circulating and predictive biomarkers in sarcomatoid renal cell carcinoma

Talal El Zarif, Karl Semaan, Marc Eid, Ji-Heui Seo, Simon Garinet, Matthew P. Davidsohn, Pranshu Sahgal, Brad J. Fortunato, John Canniff, Amin H. Nassar, Sarah Abou Alaiwi, Ziad Bakouny, Gitanjali Lakshminarayanan, Hunter Savignano, Kevin Lyons, , Sylvan C. Baca

The paper identifies epigenomic signatures in sarcomatoid renal cell carcinoma (sRCC) that predict response to immune checkpoint inhibitors and are detectable in plasma, enabling non-invasive diagnosis.

Cell Reports · Jun 1, 2024Peer-reviewedGenomics