Cancer BiologyGastroenterologyPeer-reviewed
Chemical perturbations impacting histone acetylation governcolorectal cancer differentiation
Pornlada Likasitwatanakul, Zhixin Li, Khoa Tat Doan…·Nilay S. Sethi
The paper identifies HDAC1/2 inhibition as a method to promote colorectal cancer differentiation through H3K27ac gains, which can be reversed by blocking EP300.
9 citations