ImmunologybioRxivPreprint
Protecting Allogeneic Pancreatic Islet Grafts by Engineered Veto
Yan Qi, Xianghua Zhang, Paula Konigsberg…·Uwe D. Staerz
This study uses adenoviral vectors to express CD8-TCR chains in pancreatic islets, enabling them to induce immune tolerance and protect against rejection without systemic immunosuppression.
2 citations