Neuropeptide Y deficiency in the bone marrow drives hematopoietic stem and progenitor cell aging
Dinisha Kamble, James P. Ropa, Malgorzata Maria Kamocka, Yan Qi, Nick R. Imperiale, Pratibha Singh
This study shows that neuropeptide Y deficiency in the bone marrow drives hematopoietic stem and progenitor cell aging, and NPY supplementation can reverse age-related defects.
bioRxiv · Feb 20, 2026 · PreprintCell Biology