Design of post-translational, ligand-controlled inverters and switches
Samuel D. Swift, Kieran S McCarthy, Zachary T. Baumer, Ian R. Wheeldon, Sean R. Cutler, Timothy A. Whitehead
The paper designs and engineers minimal protein-based molecular inverters and switches that respond to ligands, demonstrating tunable and modular control of post-translational signaling.
bioRxiv · Dec 6, 2025 · PreprintSynthetic Biology