GATA6 regulates WNT and BMP programs to pattern precardiac mesoderm during the earliest stages of human cardiogenesis
Joseph A. Bisson, Miriam Gordillo, Ritu Kumar, Neranjan de Silva, Ellen Yang, Kelly M. Banks, Zhong‐Dong Shi, Kihyun Lee, Dapeng Yang, Wendy K. Chung, Danwei Huangfu, Todd Evans
This study shows GATA6 regulates WNT and BMP programs in human precardiac mesoderm patterning, and modulating these pathways can rescue cardiomyocyte defects in GATA6 mutants.
eLife · Mar 13, 2025Peer-reviewedDevelopmental Biology